Diabetes is a hormone disorder that can cause problems with the kidneys, legs and feet, eyes, heart, nerves, and blood flow.Diabetes can cause many complications. Acute complications (hypoglycemia, ketoacidosis or nonketotic hyperosmolar coma) may occur if the disease is not adequately controlled. Diabetes is on the increase, probably because people are living longer, getting fatter and leading increasingly inactive lifestyles. Diabetes, without qualification, usually refers to diabetes mellitus, but there are several rarer conditions also named diabetes. The most common of these is diabetes insipidus in which the urine is not sweet; it can be caused by either kidney or pituitary gland damage. The term “type 1 diabetes” has universally replaced several former terms, including childhood-onset diabetes, juvenile diabetes, and insulin-dependent diabetes. “Type 2 diabetes” has also replaced several older terms, including adult-onset diabetes, obesity-related diabetes, and non-insulin-dependent diabetes. About 3 to 8 percent of pregnant women in the United States develop gestational diabetes.

Diabetes can also cause heart disease, stroke and even the need to remove a limb. Pregnant women can also get diabetes, called gestational diabetes. Type 1 diabetes mellitus—formerly known as insulin-dependent diabetes (IDDM), childhood diabetes. Type 2 diabetes mellitus—previously known as adult-onset diabetes, maturity-onset diabetes, or non-insulin-dependent diabetes mellitus (NIDDM). Symptoms of Type 2 diabetes may include fatigue, thirst, weight loss, blurred vision and frequent urination. Some people have no symptoms. A blood test can show if you have diabetes. Exercise, weight control and sticking to your meal plan can help control your diabetes. Most people affected by type 1 diabetes are otherwise healthy and of a healthy weight when onset occurs. Diet and exercise cannot reverse or prevent type 1 diabetes. Gestational diabetes is caused by the hormones of pregnancy or a shortage of insulin. Women with gestational diabetes may not experience any symptoms.

Diabetes mellitus is characterized by recurrent or persistent hyperglycemia. Diabetes affects more than 20 million Americans. About 54 million Americans have prediabetes. Medications have also been shown to provide similar benefit. Both diabetes drugs metformin and Precose have been shown to prevent the onset of type 2 diabetes in people with this pre-diabetes condition. A group of medicines known as ACE (angiotensin converting enzyme) inhibitors are sometimes used to reduce the risk of developing cardiovascular complications in diabetes and can also reduce the risk or progression of kidney and eye diseases. Microscopic or nanotechnological approaches are under investigation as well, in one proposed case with implanted stores of insulin metered out by a rapid response valve sensitive to blood glucose levels. Medications to treat diabetes include insulin and glucose-lowering pills called oral hypoglycemic drugs. Insulin preparations differ in how quickly they start to work and how long they remain active. Stop smoking, which hinders blood flow to the feet.

Diabetes Treatment and Prevention Tips

1. Diabetes is usually controlled by a healthy diet and regular exercise.

2. Magnesium may play a significant role in preventing Type 2 diabetes.

3. Use of metformin, rosiglitazone and valsartan.

4. Exercise, weight control and sticking to your meal plan can help control your diabetes.

5. Glucose in the blood is produced by the liver from the foods you eat.

6. Oral medications are still insufficient, insulin medications are considered.

7. Maintaining an ideal body weight and an active lifestyle may prevent the onset of type 2 diabetes.

8. Strict control of blood glucose, or blood sugar, as well as blood pressure

Bhupesh Chandra Semwal 1* Sonia Singh1, Dr. Kalyani Divakar2

Introduction-Diabetes mellitus often referred to simply as diabetes. Diabetes is a syndrome characterized by disordered metabolism and abnormally high blood sugar, hyperglycemia resulting from insufficient levels of the hormone insulin. The world health organization recognizes three main forms of diabetes mellitus type1 type2 and gestational diabetes. Gestational diabetes occurring during pregnancy. Which have different causes and population distributions. While, ultimately, all forms are due to the beta cells of the pancreas being unable to produce sufficient insulin to prevent hyperglycemia, the causes are different. All types have been treatable since insulin became medically available in 1921. Type 1 diabetes, in which insulin is not secreted by the pancreas, is directly treatable only with injected insulin, although dietary and other lifestyle adjustments are part of management. Type 2 may be managed with a combination of dietary treatment, tablets and injections and, frequently, insulin supplementation. While insulin was originally produced from natural sources such as porcine pancreas, most insulin used today is produced through genetic engineering, either as a direct copy of human insulin, or human insulin with modified molecules that provide different onset and duration of action. Insulin can also be delivered continuously by a specialized pump which subcutaneously provides insulin through a changeable catheter1.

Classification of diabetes-

Type one diabetes mellitus

Type two diabetes mellitus

Gestational diabetes mellitus2

Signs and symptoms-

Frequent urination, Excessive thirst, Extreme hunger, unusual weight loss, Increased fatigue, Irritability, Blurry vision 3

Top Risk Factors for Type 2 Diabetes

Obesity

An excessively high body weight increases diabetes risk. The Body Mass Index ( BMI) is a simple, widely accepted means of assessing body weight in relation to health for most people aged 20 to 65 (Exceptions include people who are very muscular, athletes, pregnant or nursing.) A BMI greater than 27 indicates a risk for developing type 2 diabetes and other health problems which include cardiovascular disease, and premature death.

Apple-shaped figure

Individuals who carry most of their weight in the trunk of their bodies (i.e., above the hips) tend to have a higher risk of diabetes than those of similar weight with a pear-shaped body (excess fat carried mainly in the hips and thighs). A waist measurement of more than 100 cm (39.5 inches) in men and 95 cm (37.5 inches) in women suggests an increased risk.

Sedentary lifestyle

Being overweight - another risk factor for Type 2 - can be prevented by regular physical activity. A second, independent benefit of regular physical activity is improved blood sugar control in persons who already have type 2 diabetes.

Unhealthy Eating Habits

Ninety% of people who have been diagnosed with type 2 diabetes are overweight. Unhealthy eating contributes largely to obesity. Too much fat, not enough fiber, and too many simple carbohydrates all contribute to a diagnosis of diabetes. Eating right is can turn the diagnosis around and reverse or prevent Type 2.

Increased Age

            It’s a sad but true fact. Age increases the risk of type 2 diabetes.  The older we get, the greater our risk of type 2 diabetes. Even if an elderly person is thin, they still may be predisposed to getting diabetes. Scientists theorize that the pancreas ages right along with us, and doesn’t pump insulin as efficiently as it did when we were younger. Also, as our cells age, they become more resistant to insulin as well.

 High Blood Pressure and High Cholesterol

            High BP and high cholesterol are the hallmark risk factors for many diseases and conditions, including type 2 diabetes. More than 40 percent of people with diabetes have abnormal levels of cholesterol and similar fatty substances that circulate in the blood. These abnormalities appear to be associated with an increased risk of cardiovascular disease among persons with diabetes.

Family History and Genetics

            It appears that people who have family members who have been diagnosed with type 2 diabetes are at a greater risk for developing it themselves. African Americans, Hispanic-Americans and Native Americans all have a higher than normal rate of type 2 diabetes.

History of Diabetes in Pregnancy

            Nearly 40 percent of the women who have diabetes during their pregnancy go on to develop type 2 diabetes later, usually within five to ten years of giving birth. Giving birth to a baby that weighs more than nine pounds (4 kg) is another symptom of gestational diabetes.

Impaired Glucose Tolerance

            Impaired glucose tolerance or impaired fasting glucose can precede the development of type 2 diabetes. These conditions are determined through blood tests. While persons affected with these problems do not meet the diagnostic criteria for diabetes, their blood sugar control and reaction to sugar loads are considered to be abnormal. This places them at higher risk, not just for the development of type 2 diabetes (an estimated one in ten progress to type 2 diabetes within five years), but also for cardiovascular disease. For this group, preventive strategies including lifestyle changes and regular screening for diabetes mellitus must be a priority4.

Alternative medicine for treatment of diabetes-

 Ginseng -Although there are several different types of ginseng, most of the promising studies on ginseng and diabetes have used North American ginseng (Panax quinquefolius). Those studies have shown that North American ginseng may improve blood sugar control and glycosylated hemoglobin (a form of hemoglobin in the blood used to monitor blood glucose levels over time) levels.

 Chromium-    Chromium is an essential trace mineral that plays an important role in carbohydrate and fat metabolism and helps body cells properly respond to insulin.

 Magnesium-  Magnesium is a mineral found naturally in foods such as green leafy vegetables, nuts, seeds, and whole grains and in nutritional supplements.Magnesium is needed for more than 300 biochemical reactions. It helps regulate blood sugar levels and is needed for normal muscle and nerve function, heart rhythm, immune function, blood pressure, and for bone health. Some studies suggest that low magnesium levels may worsen blood glucose control in type 2 diabetes. There is also some evidence that magnesium supplementation may help with insulin resistance.

Cinnamon-Cinnamon is a glycosides it improves blood glucose control in people with type 2 diabetes.

 Zinc-   The mineral zinc plays an important role in the production and storage of insulin. There is some research showing that people with type 2 diabetes have suboptimal zinc status due to decreased absorption and increased excretion of zinc. Food sources of zinc include fresh oysters, ginger root, lamb, pecans, split peas, egg yolk, rye, beef liver, lima beans, almonds, walnuts, sardines, chicken, and buckwheat.

 Aloe Vera Gel-Although aloe vera gel is better known as a home remedy for minor burns and other skin conditions, recent animal studies suggest that aloe vera gel may help people with diabetes. A Japanese study evaluated the effect of aloe vera gel on blood sugar. Researchers isolated a number of active phytosterol compounds from the gel that were found to reduce blood glucose and glycosylated hemoglobin levels.

Gymnema- Several preliminary studies suggest that the herb gymnema can lower blood sugar levels in people with type 2 diabetes. Because gymnema may lower blood sugar levels, people taking medications for diabetes or using insulin shouldn’t take gymnema unless they are closely monitored by their health care provider

Vanadium-Vanadium is a trace mineral found naturally in soil and many foods. It is also produced during the burning of petroleum. Vanadium has been found to improve insulin sensitivity and reduce blood sugar in people with type 2 diabetes. It appears to mimic many of the actions of insulin in the body. The use of vanadium for diabetes, particularly without the supervision of a qualified health care practitioner, is not recommended, because the dose needed to affect blood glucose levels can be potentially toxic. The typical amount of vanadium found in the average diet (less than 30 micrograms per day) appears to have little toxicity5.

Neem- The leaves of Neem posses’ anti-diabetic properties. The juices of these leaves are helpful in controlling the blood sugar level in diabetics. Neem is in fact an herbal medicine used for the treatment of various other diseases also such as skin problems, warm infections, ulcer etc.

Sweet potato leaves- The leaves of sweet potato are high value in preventing diabetes, by lowering blood sugar level. It is highly nutritious vegetable. Preparation of sweet potato leaves is used in the tea of diabetic patients.

Madhuca- The Indian name for Madhuca is Madhua it is also posses’ excellent anti-diabetic properties and it is highly beneficial in treating raised blood sugar levels.

Mango leaves- The leaves of Mango helps in lowering the blood sugar levels in diabetics. The fresh leaves of mango are socked in water for an overnight. Then they are squeezed well in the water before filtering them in the morning6.

 Discussion and Conclusion- Managements of diabetes with the agents devoid of any side effects is still challenge for the medical system. This has lead to increase in the demand for natural products with antihyperglycemic activity having fewer side effects. Metabolic imbalance causing diabetes mellitus is a characteristic of materialistic world. Differences in social structure, psychic stress, obesity, hormonal imbalance and heredity are optimizing the growth of pandemic. Increasing population with diabetes has a huge requirement of effective remediation. The vast variety of medicinal plants, which are used traditionally for their anti-diabetic property. However, careful assessment including sustainability of such herbs, ecological and seasonal variation in activity of phyto-constituents, metal contents of crude herbal anti-diabetic drugs, thorough toxicity study and cost effectiveness is required for their popularity. These efforts may provide treatment for all and justify the role of novel traditional medicinal plants having anti-diabetic potentials.

 

References

http://www.diabetesmellitus-information.com/diabetes_herbs.htm

http://www.umm.edu/ency/article/002072.htm

http://www.diabetes.org/diabetes-symptoms.jsp

http://www.phac-aspc.gc.ca/ccdpc-cpcmc/diabetes-diabete/english/risk/index.html

http://altmedicine.about.com/cs/conditionsatod/a/Diabetes.htm

http://www.diabetesmellitus-information.com/diabetes_treatment.htm

 

Diabetes is an insulin-related disease that affects nearly 21 million people in the USA. This grave situation is characterized by the bodys inability to produce enough using the services or insulin. It is the hormone, insulin, which is responsible for hot flashes from glucose into the cells of the body. When blood sugar rises, our health suffers greatly.

According to the National Diabetes Information Clearinghouse (NDIC), about 14.6 million people in the USA are diagnosed with the disease, while nearly 6 million people have not yet been diagnosed. In a 2005 NDIC report, the total results with regard to diabetes patients of all ages, from those of the elderly to experience toddlers May symptoms of diabetes. Typically, type 2 diabetes who suffer are usually diagnosed between the ages of 35 and 50.

The symptoms of diabetes

There are many signs that alert a person that May be suffering from diabetes. Common symptoms of diabetes May occur in bulk or a patient May an exhibition only a few. Whatever the case May, when any of the following diabetes symptoms appear, patients should contact their doctor.

Individuals should be on the lookout for: frequent urination, extreme hunger or thirst, blurred vision, sudden weight loss, numbness or tingling in the hands or feet, fatigue, skin too dry, increased infections and slow healing of wounds. People with type 1 diabetes symptoms include nausea, vomiting and / or abdominal pain.

Different types of diabetes

If you experience symptoms that prove the disease, it will be diagnosed as suffering either type 1 or type 2 diabetes. Type 1 diabetes accounts for 5-10% of diagnosed cases of diabetes where the immune system actually destroys the cells in the body that produce insulin. This type of diabetes May also be regarded as insulin-dependent diabetes or juvenile-onset diabetes. Most people with the disease are diagnosed with type 2 diabetes, which involves the bodys resistance to insulin. Another type of diabetes exists, but only affects 2-5% of pregnant women. It is called gestational diabetes and has the potential to harm the mother and child when they are not treated.

From Diabetes

When accompanied by regular exercise and proper medication, healthy eating habits can relieve the symptoms of diabetes. Thanks to a balanced diet, filled with a healthy mix of carbohydrates, proteins and fats, good nutrition can be used as a defence against the symptoms associated with diabetes. Acceptable foods include fruits, vegetables, whole grains, poultry, beans, milk 2% and lean meats. The fried foods and very sweet foods should be avoided if diagnosis of diabetes.

Demand for treatment is important

When you think you are exhibiting symptoms of diabetes, an immediate visit to a doctor is required. The reason is that when diabetes is not treated, a host of debilitating health problems follows closely. Since foot problems tend to affect diabetics, there are many concerns in this area, including infection, gangrene and amputation. The eye problems are also common in people with diabetes. When left untreated, blindness May occur. Other health problems associated with diabetes untreated symptoms include heart disease and renal failure. The disease is so serious that it is a major cause of death in the USA.

Finding out you or someone you love has diabetes is scary. But don’t panic. Diabetes is serious, but people with diabetes can live long, healthy, happy lives.

The cause of diabetes continues to be a mystery, although both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

There are two major types of diabetes. Type 1 diabetes results from the body’s failure to produce insulin, the hormone that “unlocks” the cells of the body, allowing glucose to enter and fuel them. It is estimated that 5-10% of Americans who are diagnosed with diabetes have type 1 diabetes. Type 2 diabetes results from insulin resistance (a condition in which the body fails to properly use insulin), combined with relative insulin deficiency. Most Americans who are diagnosed with diabetes have type 2 diabetes.

There is also pre-diabetes which is a condition that occurs when a person’s blood glucose levels are higher than normal but not high enough for a diagnosis of type 2 diabetes. There are 54 million Americans who have pre-diabetes, in addition to the 20.8 million with diabetes.

Diabetes symptoms may vary from person to person but most of the time anyone with diabetes will experience some or all of these symptoms. Some symptoms are: going to the restroom more often, staying thirsty, fatigue, blurred vision, stomach pain and occasionally people suffer from weight loss.

Type 1 diabetes is normally only found in children and type 2 diabetes is found mostly in adults but not always. There are some cases where children are being diagnosed with type 2 diabetes. Some people may be diagnosed with being borderline diabetic, which normally ends up turning into full blown diabetes but not always.

Some of the most important things people with diabetes should know is a healthy, nutritional diet and a regular exercise program can help in treating the disease. Speak with your doctor about what kind of diet you should consider following, along with a moderate exercise program. The doctor or a nutritionist should be able to tell you exactly what kinds of foods you should be avoiding and give you some tips on how much exercise you need every week. Doing this has many health benefits and will also make you feel so much better about yourself.

You should know the truth about some of the most common myths about diabetes. Myth #1 You can catch diabetes from someone else. No. Although we don’t know exactly why some people develop diabetes, we know diabetes is not contagious. It can’t be caught like a cold or flu. There seems to be some genetic link in diabetes, particularly type 2 diabetes. Lifestyle factors also play a part.

Myth #2 People with diabetes can’t eat sweets or chocolate. If eaten as part of a healthy meal plan, or combined with exercise, sweets and desserts can be eaten by people with diabetes. They are no more “off limits” to people with diabetes, than they are to people without diabetes.

Myth #3 Eating too much sugar causes diabetes. No. Diabetes is caused by a combination of genetic and lifestyle factors. However, being overweight does increase your risk for developing type 2 diabetes. If you have a history of diabetes in your family, eating a healthy meal plan and regular exercise are recommended to manage your weight.

Myth #4 People with diabetes should eat special diabetic foods. A healthy meal plan for people with diabetes is the same as that for everyone